Cognitive Reflection Test (CRT) Practice 2026 - Free Cognitive Reflection Test Practice Questions and Study Guide

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What is the mechanism of action for levodopa therapy in patients with Parkinson disease?

Increases serotonin levels in the brain

Blocks dopamine receptors

Restores dopamine levels in the brain

Levodopa therapy is designed to address the deficiency of dopamine, a crucial neurotransmitter that is significantly reduced in individuals with Parkinson's disease. The mechanism of action for levodopa involves its conversion to dopamine in the brain. When administered, levodopa crosses the blood-brain barrier and is subsequently converted into dopamine by the enzyme aromatic L-amino acid decarboxylase. By restoring dopamine levels, levodopa effectively alleviates the motor symptoms associated with Parkinson's disease, such as tremors, rigidity, and bradykinesia.

This is fundamental to the treatment of Parkinson's, as the disease is characterized by the death of dopamine-producing neurons in a part of the brain called the substantia nigra. The restoration of dopamine through levodopa helps improve the patient's motor control and overall quality of life, making it a cornerstone of Parkinson's disease management. In contrast, the other options do not align with the primary therapeutic goals of levodopa or its physiological effects.

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Inhibits acetylcholine activity

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